The Sepsis Hypothesis

The physician advised us on how sepsis is determined by summarizing Septic Shock.

Septic shock, a subset of sepsis, is a severe condition that can possibly occur should sepsis lead to life-threatening hypo tension for a patient. The human body would possess the following attributes if they are in septic shock.

Body Attribute	Body Attribute Value Required for Septic Shock
Body temperature	<36 °Celsius or  >38 °Celsius
Heart rate	>90 BPM
Respiratory rate	>20 BPM or arterial CO2 pressure (PaCO2) <32 mmHg
White blood cell count	<4,000/mL or >12,000/mL

Severe sepsis, being the presence of sepsis in together with sepsis-related organ dysfunction, is also shown.

Body Attribute	Body Attribute Value Required for Septic Shock
Systolic blood pressure	<90 mmHg
Blood Lactate	>2.0 mmol/L
Urine output	<0.5 mL/kg over the last two hours despite adequate fluid resuscitation
Creatinine	>2.0 mg/dL without the presence of chronic dialysis or renal insufficiency

The physician also assessed the eICU database in order to help us pick out valuable data attributes that we would need in predicting sepsis.

Data Attribute	Database File
patientunitstayid	Table 18: patient.csv Cleaned File Description
observationoffset	Table 18: patient.csv Cleaned File DescriptionTable 12: patient.csv File Description
temperature	Table 21: vitalPeriodic.csv Cleaned File Description
heartrate	Table 21: vitalPeriodic.csv Cleaned File Description
respiration	Table 21: vitalPeriodic.csv Cleaned File Description
systemicsystolic	Table 21: vitalPeriodic.csv Cleaned File Description
wbcx1000	Table 19: lab.csv Cleaned File Description
lactate	Table 19: lab.csv Cleaned File Description
creatinine	Table 19: lab.csv Cleaned File Description
urineoutputbyweight	Table 20: intakeOutputUrine.csv File Description
diagnosis	Table 16: diagnosis.csv Cleaned File Description

If we can indeed use these values to train the model, then our predictions would be successful.